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                6-Methyl-1,2,3-oxathiazin-4(3H)-on-2,2-dioxid, Kaliumsalz Produkt Beschreibung

                AcesulfaMe Struktur
                55589-62-3
                • CAS-Nr.55589-62-3
                • Bezeichnung:6-Methyl-1,2,3-oxathiazin-4(3H)-on-2,2-dioxid, Kaliumsalz
                • Englisch Name:AcesulfaMe
                • Synonyma:6-Methyl-1,2,3-oxathiazin-4(3H)-on-2,2-dioxid, Kaliumsalz
                  sunett;SUNETTE;SWEET ONE;acesulfame;Ccris 1032;ACESULFAME K;Acesulfaml-K;Acessulfame-K;ACESULPHAME-K;ACESULFAME-K(P)
                • CBNumber:CB3224119
                • Summenformel:C4H5KNO4S
                • Molgewicht:202.25
                • MOL-Datei:55589-62-3.mol
                6-Methyl-1,2,3-oxathiazin-4(3H)-on-2,2-dioxid, Kaliumsalz physikalisch-chemischer Eigenschaften
                • Schmelzpunkt: :229-232°C (dec.)
                • Dichte :(solid) 1.81 g/cm3; d (bulk) 1.1-1.3 kg/dm3
                • storage temp.  : 0-6°C
                • L?slichkeit :Soluble in water, very slightly soluble in acetone and in ethanol (96 per cent).
                • Aggregatzustand :neat
                • Wasserl?slichkeit :almost transparency
                • Merck  :14,37
                • BRN  :3637857
                • CAS Datenbank :55589-62-3(CAS DataBase Reference)
                • EPA chemische Informationen :Acesulfame-potassium (55589-62-3)
                Sicherheit
                • R-S?tze: :36/37/38
                • S-S?tze: :26-36/37/39
                • WGK Germany  :1
                • RTECS-Nr. :RP4489165
                • HS Code  :2934990002
                • Toxizit?t :LD50 in rats (mg/kg): 7431 orally, 2243 i.p. (Mayer, Kemper)

                AcesulfaMe Chemische Eigenschaften,Einsatz,Produktion Methoden

                • R-S?tze Betriebsanweisung: R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
                • S-S?tze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
                  S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
                • Chemische Eigenschaften White to Off-White Solid
                • Chemische Eigenschaften Acesulfame potassium occurs as a colorless to white-colored, odorless, crystalline powder with an intensely sweet taste.
                • Verwenden Potassium salt as sweetener for foods, cosmetics.
                • Verwenden 'New generation', heat-stable sweetener that has not been suspected to cause cancer nor be genotoxic. Allelic variation of the Tas1r3 gene affects behavioral taste responses to this molecule, suggesting that it is a T1R3 receptor ligand.
                • Verwenden Acesulfame-K is the potassium salt of 6-methyl-l,2,3-oxathiazin-4(3H)- one-2,2-dioxide. This sweetener was discovered in Germany and was first approved by the FDA in 1988 for use as a nonnutritive sweetener. The complex chemical name of this substance led to the creation of the trademark common name, acesulfame-K, which is based on its following relationships to acetocetic acid and sulfanic acid, and to its potassium salt nature.
                  Acesulfame-K is 200 times as sweet as sugar and is not metabolized and is thus noncaloric. It is exceptionally stable at elevated temperatures encountered in baking, and it is also stable in acidic products, such as carbonated soft drinks. It has a synergistic effect when mixed with other low-calorie sweetners, such as aspartame. Common applications of acesulfame-K are table uses, chewing gums, beverages, foods, bakery products, confectionary, oral hygiene products, and pharmaceuticals.
                • Vorbereitung Methode Acesulfame potassium is synthesized from acetoacetic acid tertbutyl ester and fluorosulfonyl isocyanate. The resulting compound is transformed to fluorosulfonyl acetoacetic acid amide, which is then cyclized in the presence of potassium hydroxide to form the oxathiazinone dioxide ring system. Because of the strong acidity of this compound, the potassium salt is produced directly.
                  An alternative synthesis route for acesulfame potassium starts with the reaction between diketene and amidosulfonic acid. In the presence of dehydrating agents, and after neutralization with potassium hydroxide, acesulfame potassium is formed.
                • Pharmazeutische Anwendungen Acesulfame potassium is used as an intense sweetening agent in cosmetics, foods, beverage products, table-top sweeteners, vitamin and pharmaceutical preparations, including powder mixes, tablets, and liquid products. It is widely used as a sugar substitute in compounded formulations,and as a toothpaste sweetener.
                  The approximate sweetening power is 180–200 times that of sucrose, similar to aspartame, about one-third as sweet as sucralose, one-half as sweet as sodium saccharin, and about 4-5 times sweeter than sodium cyclamate.It enhances flavor systems and can be used to mask some unpleasant taste characteristics.
                • Sicherheit(Safety) Acesulfame potassium is widely used in beverages, cosmetics, foods, and pharmaceutical formulations, and is generally regarded as a relatively nontoxic and nonirritant material. Pharmacokinetic studies have shown that acesulfame potassium is not metabolized and is rapidly excreted unchanged in the urine. Long-term feeding studies in rats and dogs showed no evidence to suggest acesulfame potassium is mutagenic or carcinogenic.
                  The WHO has set an acceptable daily intake for acesulfame potassium of up to 15 mg/kg body-weight.The Scientific Committee for Foods of the European Union has set a daily intake value of up to 9 mg/kg of body-weight.
                  LD50 (rat, IP): 2.2 g/kg
                  LD50 (rat, oral): 6.9–8.0 g/kg
                • Lager Acesulfame potassium possesses good stability. In the bulk form it shows no sign of decomposition at ambient temperature over many years. In aqueous solutions (pH 3.0–3.5 at 208℃) no reduction in sweetness was observed over a period of approximately 2 years. Stability at elevated temperatures is good, although some decomposition was noted following storage at 408℃ for several months. Sterilization and pasteurization do not affect the taste of acesulfame potassium.
                  The bulk material should be stored in a well-closed container in a cool, dry place and protected from light.
                • Regulatory Status Included in the FDA Inactive Ingredients Database for oral and sublingual preparations. Included in the Canadian List of Acceptable Non-medicinal Ingredients. Accepted for use in Europe as a food additive. It is also accepted for use in certain food products in the USA and several countries in Central and South America, the Middle East, Africa, Asia, and Australia.
                AcesulfaMe Upstream-Materialien And Downstream Produkte
                Upstream-Materialien
                Downstream Produkte
                6-Methyl-1,2,3-oxathiazin-4(3H)-on-2,2-dioxid, Kaliumsalz Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
                Global(278)Suppliers
                • Firmenname:Shanghai Boyle Chemical Co., Ltd.
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                55589-62-3, AcesulfaMe Verwandte Suche:
                • acesulfame
                • Acessulfame-K
                • 1,2,3-oxathiazin-4(3h)-one,6-methyl-,2,2-dioxide,potassiumsalt
                • 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one2,2-dioxidepotassiumsalt
                • potassiumacesulfame
                • Potassiumsaltof6-methyl-1,2,3-oxathiazin-4(3H)-one-2,2-dioxide
                • sunett
                • Acesulfamum Kalicum
                • ACESULFAME-K FCC 99-101%
                • ACESULFAME-K(P)
                • AcesulfaMe PotassiuM,NF
                • PotassiuM 6-Methyl-4-oxo-4H-1,2,3-oxathiazin-3-ide 2,2-dioxide
                • 1,2,3-Oxathiazin-4(3H)-one, 6-methyl-, 2,2-dioxide, potassium salt (1:1)
                • SUNETTE
                • SWEET ONE
                • RARECHEM AM UC 0205
                • POTASSIUM 6-METHYL-1,2,3-OXATHIAZIN-4(3H)-ONE 2,2-DIOXIDE
                • 6-METHYL-1,2,3-OXATHIAZIN-4(3H)-ONE 2,2-DIOXIDE POTASSIUM SALT
                • ACESULFAME K
                • ACESULFAME POTASSIUM SALT
                • ACESULFAME POTASSIUM
                • ACESULFAME POTASSIUM(AK)
                • ACESULPHAME-K
                • POTASSIUMACESULFAMEK
                • ASPARTAMEACESULPHAMESALT
                • ACESULPHAMEPOTASSIUM
                • 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid, Kaliumsalz
                • Blended sweetener of acesulfame-kwith aspartame
                • Acesulfaml-K
                • 3,4-Dihydro-6-methyl-3-potassio-4-oxo-1,2,3-oxathiazine 2,2-dioxide
                • 3,4-Dihydro-6-methyl-4-oxo-3-potassio-1,2,3-oxathiazine 2,2-dioxide
                • Ccris 1032
                • Einecs 259-715-3
                • Acesulfame K,6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt
                • Acesulfame Potassium (200 mg)
                • 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-Dioxide Potassium Salt Potassium 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-Dioxide
                • 55589-62-3
                • C4H4NO4KS
                • C4H4NO4SKC4H4KNO4S
                • C4H4KNO4S
                • C4H5NO4SK
                • C4H5KNO4S
                • C4H4SNKO4
                • C4H4SKNO4
                • C4H4KNSO4
                • Typical Metal Compounds
                • Classes of Metal Compounds
                • K (Potassium) Compounds (excluding simple potassium salts)
                • Sweetener
                • Food &amp; Beverage Standards
                • Chromatography
                • Analytical Standards
                • Analytical Chromatography Product Catalog
                • -
                • SUNETT
                • Food & Feed ADDITIVES
                • K (Potassium) Compounds (excluding simple potassium salts)
                • Classes of Metal Compounds